As for this invention, formula (i) below (in formula, Cy and ring A, m, as for n, p, R, R, R, R, R, and R as in definition are) the chemical compound which is 4 integurinantagonisuto which possesses structure or the blend of the tautomerization isomer and tautomerization isomer, the salt, or the solvent dishes dressed with sauce are offered in the bill. As for this invention, furthermore, the pharmacy composition which includes the chemical compound of this invention, and, for example, various conditions and obstacle (the chemical compound of this invention in) disposal and preventing such as the clone illness and the ulcer characteristic large enteritis and production method and usage of the composition are offered.本発明は、以下の式(I)(式中、Cy、環A、m、n、p、R1、R2、R3、R4、R5、およびR6は明細書中に定義の通りである)の構造を有するα4インテグリンアンタゴニストである化合物またはその互変異性体、互変異性体の混合物、塩、もしくは溶媒和物を提供する。本発明は、さらに、本発明の化合物を含む薬学的組成物、ならびに、例えば、種々の容態および障害(クローン病および潰瘍性大腸炎など)の処置および防止における本発明の化合物および組成物の作製方法および使用方法を提供する。
