Yat Sun Or,Xuechao Xing,Ruichao Shen,Bin Wang,Brett Granger,Jun Ma,Jing He,Jiang Long,Yong He,Guoqiang Wang
申请号:
US15597431
公开号:
US20170333399A1
申请日:
2017.05.17
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention provides compounds of Formula I:and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising these compounds and methods of using these compounds to treat or prevent a disease or disorder mediated by FXR. Specifically, the present invention relates to isoxazole derivatives useful as agonists for FXR and methods for their preparation and use.