UNIVERSITY OF MIAMI;U.S.A., REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
发明人:
Andrew Schally,Joshua M. Hare,Norman Block,Samirah Gomes,Rosemeire M. Kanashiro-Takeuchi
申请号：
US15820079
公开号：
US20180250358A1
申请日:
2017.11.21
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Disclosed herein are compositions of GHRH agonists and peptides, and methods to treat disorders, such as ischemia and reperfusion injury. In one embodiment, a method of treating a reperfusion injury in a subject in need may involve administering a therapeutically effective amount of at least one GHRH agonist peptide to the subject. In additional embodiment, a method of promoting vasculogenesis in a mammal may involve administering a therapeutically effective amount of at least one GHRH agonist peptide to the subject. In a further embodiment, a method of promoting differentiation of mesenchymal stem cells into endothelial cells may involve contacting mesenchymal stem cells with at least one GHRH agonist peptide.
