An organizer anchor assembly may include an organizer unit coupled to an anchor base having a flat bottom with sufficient surface area in contact with a table or other surface to secure the organizer assembly in place during use. The organizer unit holds and organizes lines of a medical device, such as a peritoneal dialysis machine. The anchor base may be flat to contact the cart or table surface and/or may include a perpendicular portion designed to wrap around an edge of the cart or table surface. The organizer anchor assembly may be beneficially used in connection with a home dialysis machine in which lines and connectors are desirably organized and anchored during a dialysis treatment. Portions of the organizer anchor assembly may be made of polymer materials that provide a frictional interface in contact with a surface to resist movement of the organizer anchor assembly across the surface.