LANTTO, JOHAN,ANDERSEN, KIM, VILBOUR,ANDERSEN, PETER, SEJR,STRANDH, MAGNUS,KOEFOED, KLAUS,NIELSEN, LARS, SOGAARD,PEDERSEN, MIKKEL, WANDAHL,JACOBSEN, HELLE,KRAGH, MICHAEL,KJAER, IDA,POULSEN, THOMAS, TU
申请号:
HK15103006.9
公开号:
HK1202431A
申请日:
2015.03.24
申请国别(地区):
HK
年份:
2015
代理人:
摘要:
The invention relates to humanized recombinant antibodies targeting the EGFR family receptors EGFR, HER2 and HER3, compositions comprising at least one humanized anti-EGFR antibody, at least one humanized anti-HER2 antibody and at least one humanized anti-HER3 antibody, and use of the antibody compositions for treatment of cancer. The invention also relates to the use of antibodies targeting multiple EGFR-family receptors to treat cancer (e.g., pancreatic cancer) and cancer that has acquired resistance to previous therapies.