Annelise E. Barron;Ronald N. Zuckermann;Cindy W. Wu
发明人:
Annelise E. Barron,Ronald N. Zuckermann,Cindy W. Wu
申请号：
US11120071
公开号：
US08114830B2
申请日:
2005.05.02
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention provides spreading agents based on sequence-specific oligomers comprising a peptoid, a peptide-peptoid chimera, a retropeptoid or a retro(peptoid-peptide) chimera, and methods for using the same, including for the treatment of respiratory distress of the lungs. The spreading agents are sequence-specific oligomers, including retrosequence-specific oligomers, based on a peptide backbone, that are designed as analogs of surfactant protein-B or surfactant protein-C.
