The invention generally relates to systems for imaging and monitoring endoluminal valve formation. In certain aspects, a system of the invention includes: an elongate body defining a lumen and an exit port located on a side of the elongate body, wherein the side of the elongate body is configured to engage with a vessel wall a tissue dissection probe disposed within the lumen, and configured to extend out of the exit port and into the vessel wall in order to form an intramural space in the vessel wall and an imaging element located on the tissue dissection probe.
