UNIVERSITY OF FLORIDA RESEARCH FOUNDATION; INCORPORATED
发明人:
Sahba MOBINI,Christine E. SCHMIDT,Anthony B. BRENNAN,Cary A. KULIASHA,Jack JUDY
申请号：
US16485685
公开号：
US20200054875A1
申请日:
2018.02.13
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Tissue-engineered nerve scaffolds, articles for up-selecting desired cell proliferation and down-selecting undesired cell proliferation, and methods of manufacturing the same are provided. The tissue-engineered nerve scaffold includes a hydrogel having a surface. The surface has a topography including a micropattern defined by a plurality of spaced features attached to or projected into the hydrogel. The micropattern facilitates attachment and alignment of neural cells and reduces attachment and alignment of cells associated with scar-tissue formation and encapsulation.
