B.G. NEGEV TECHNOLOGIES & APPLICATIONS LTD. AT BEN-GURION UNIVERSITY;HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT
发明人:
COHEN, SMADAR,ILAN, YARON,SHTEYER, EYAL,BEN-YA'ACOV, AMI,BEN-YAACOV, AMI
申请号：
EP13869503
公开号：
EP2938348A4
申请日:
2013.12.30
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
Compositions comprising an alginate, a source of sodium ions and a carrier (e.g., a pharmaceutically acceptable carrier), which are characterized by reduced association of the alginate chains and hence by at least one of: (i) a zeta potential weaker than −25 mV, at a concentration of 0.5% (w/v) alginate in the carrier； and (ii) a diffusion coefficient of at least 10−8 cm2/second, at a concentration of 0.5% (w/v) alginate in the carrier, are disclosed. Also disclosed are uses of the composition and methods utilizing the composition for treating inflammatory bowel disease； liver damage, diseases and disorders, for treating a medical condition treatable by a hepatotoxic agent and for reducing or preventing liver damage, including liver damage caused by a hepatotoxic agent.
