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Hydrogel Networks Having Living Cells Encapsulated Therein
专利权人:
Michael Detamore
发明人:
Michael Detamore,Stevin H. Gehrke
申请号:
US13603611
公开号:
US20120328678A1
申请日:
2012.09.05
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is directed to a hydrogel network comprised of a physically cross-linked polymer and a chemically cross-linked polymer or physically entangled copolymer containing living cells, such as chondrocytes, encapsulated therein. In a preferred aspect, the physically cross-linked polymer is selected from the group consisting of thermally gelling polysaccharides and proteins, such as agarose or gelatin, and the chemically cross-linked or physically entangled polymer is synthesized from a water-soluble vinyl monomer, either as a homopolymer or copolymer, such as polyethylene glycol diacrylate (“PEG-DA”) and 2-hydroxyethyl methacrylate (“HEMA”).
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