AMINE-BASED AND AMIDE-BASED INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) ENZYME ACTIVITY AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT OF DISEASES
JINGJING ZHAO;ERIC Y. WANG;MARY T. MACDONALD;LUISA M. SALTER-CID
发明人:
LUISA M. SALTER-CID,ERIC Y. WANG,MARY T. MACDONALD,JINGJING ZHAO
申请号：
US13414644
公开号：
US20120172392A1
申请日:
2012.03.07
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Compositions and methods are disclosed for inhibiting semicarbazide-sensitive amine oxidase (SSAO), also known as vascular adhesion protein-1 (VAP-1). The compounds disclosed are amine-containing and amide-containing compounds. The compounds and compositions are useful for treatment of diseases, including inflammation, inflammatory diseases and autoimmune disorders.
