New aminoalkoxyimino derivatives at position 3 of substituted B-homoandrostanes and B-heteroandrostanes, processes for their preparation, and to pharmaceutical compositions containing them for the treatment of cardiovascular disorders, such as heart failure and hypertension. In particular compounds having the general formula (I) are described, where the radicals have the meanings described in detail in the application.經取代B-升雄甾烷類與B-雜雄甾烷類在3-位置的新穎胺基烷氧基亞胺基衍生物、其製備方法、以及含有該等化合物而用於治療心血管疾病如心臟衰竭與高血壓之藥學組成物。特別揭示者為通式(I)之化合物;I;,其中之基團具有發明說明中所詳述之定義。