The present invention relates to retroviral constructs that encode novelmonoclonal antibodies, novel fusion proteins, and chimeric monoclonalantibodies and to methods of using and producing the same. In particular, thepresent invention relates to methods of producing a fusion protein comprisinga microorganism targeting molecule (e.g., immunoglobulin. or innate immunesystem receptor molecule) and a biocide (e.g., bactericidal enzymes) intransgenic animals (e.g., bovines) and in cell cultures. The present inventionalso relates to therapeutic and prophylactic methods of using a fusion proteincomprising a microorganism targeting molecule and a biocide in health care(e.g., human and veterinary), agriculture (e.g., animal and plant production),and food processing (e.g., beef carcass processing). The present inventionalso relates to methods of using a fusion protein comprising a microorganismtargeting molecule and a biocide in various diagnostic applications in numberof diverse fields such as agriculture, medicine, and national defense.
