Daulet Satpayev,Robert Kendall Morrison,Karen Jane Meyrick Morrison,Jean Gudas,Aya Jakobovits,Michael Torgov,Zili An
申请号:
US14798302
公开号:
US09314538B2
申请日:
2015.07.13
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Antibody drug conjugates (ADC's) that bind to 191P4D12 protein and variants thereof are described herein. 191P4D12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.