LOWELL J. BRADY,THOMAS R. BUKOWSKI,CHUNG-LEUNG CHAN
申请号:
US14476866
公开号:
US20150010500A1
申请日:
2014.09.04
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Homogeneous preparations of human and murine IL-31 have been produced by mutating one or more of the cysteine residues in the polynucleotide sequences encoding the mature proteins. The cysteine mutant proteins can be shown to either bind to their cognate receptor or exhibit biological activity.