The invention provides a cartilage repairing compound and a joint cartilage repairing method； the cartilage repairing compound comprises a platelet-rich fiber release liquid and stem cells, can promote joint cartilage regeneration, thus preventing and treating arthritis. The stem cells refer to embryonic stem cells, adult stem cells or induced pluripotent stem cells； the platelet-rich fiber protein release liquid contains at least one growth factor selected from a group formed by TGF-[beta1], VEGF, PDGF, EGF, FGF, NGF, and IGF.本發明提供一種促進關節軟骨再生之組合物、以及使用它修復關節軟骨之方法。該關節軟骨修復用組合物係包括富含血小板纖維釋放液及幹細胞，可用於促進關節軟骨再生，達到預防及治療關節炎的功效。該幹細胞係胚胎幹細胞、成體幹細胞、或誘導型多能幹細胞。該富含血小板纖維蛋白釋放液係含有從TGF-β1、VEGF、PDGF、EGF、FGF、NGF、及IGF中所選出之至少一種生長因子。
