UNIVERSITE DE MONTPELLIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;IDENIX PHARMACEUTICALS INC
发明人:
DUKHAN DAVID,STEWART ALISTAIR JAMES,MAYES BENJAMIN ALEXANDER
申请号：
AP2015008384
公开号：
AP2015008384A0
申请日:
2013.10.07
申请国别(地区):
AP
年份:
2015
代理人:
摘要：
Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, the compounds are 2&prime；-chloro nucleosides according to Formula 2001: or a pharmaceutically acceptable salt, solvate, stereoisomeric form, tautomeric form or polymorphic form thereof, wherein B, Z and PD are as described herein.
