SCHULTZ, KIMBERLY,KEATING, JENNIFER,SOLOMON, EDWARD,BECHTEL, KATE
申请号：
CA3051963
公开号：
CA3051963A1
申请日:
2018.01.30
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
A method of monitoring a time-varying fluorescence signal emitted from a fluorescent agent from within a medium with time-varying optical properties is provided that includes providing a measurement data set that includes a plurality of measurement entries that include at least two measurements obtained from a patient before and after administration of the fluorescent agent. The measurements may include one or more of: a DR ex signal detected by an unfiltered light detector during illumination by excitatory-wavelength light from first region adjacent to the diffuse reflecting medium； a Flr signal detected by a filtered light detector during illumination by excitatory-wavelength light； and a DR em signal detected by the unfiltered light detector during illumination by emission-wavelength light. The method further includes identifying a post-agent administration portion of the measurement data set； and transforming each Flr signal to an IF signal representing a detected fluorescence intensity emitted solely by the fluorescent agent.
