VARIANTS DE TYPE II DU RECEPTEUR DE TGF-BETA ET UTILISATIONS ASSOCIEES

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专利权人:

INC.;ACCELERON PHARMA

发明人:

KUMAR, RAVINDRA,GRINBERG, ASYA,SAKO, DIANNE S.,CASTONGUAY, ROSELYNE,STEEVES, RITA

申请号：

CA2921805

公开号：

CA2921805A1

申请日:

2014.08.21

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

In certain aspects, the present disclosure relates to polypeptides comprising a truncated, ligand-binding portion of the extracellular domain of ?ßR?? polypeptide useful to selectively antagonize a ?ßR?? ligand. The disclosure further provides compositions and methods for use in treating or preventing TGFß associated disorders.

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