Abstract The present invention mainly relates to pharmaceutical compositions to treat gallstones, kidney stones. In one embodiment, the herbal/medicinal composition comprising combination of therapeutically effective amount of herbal constituents/ingredients extracted from Sphaeranthus indicus L(Adakkamanian), Aerva lanata useful for the treatment of kidney stone/renal calculus/urinary stones in bladders and other urinary disorders like inflammation and urinary stent related problems without any side effects.