A system for monitoring compliance with a medication regimen comprises a patch. The patch includes an RFID apparatus and a sensor. The patch is configured to be removably securable to a body of a biological organism. The sensor is in electrical communication with the RFID apparatus and is configured to inspect a biological material of a biological organism for the presence of a detectable agent. The RFID apparatus is configured to communicate a result of the inspection to an RFID transceiver and/or a communication device. Methods are also provided.
