Pyrazolopyridine, Pyrazolopyrazine, Pyrazolopyrimidine, Pyrazolothiophene and Pyrazolothiazole Compounds as mGluR4 Allosteric Potentiators, Compositions, and Methods of Treating Neurological Dysfunction
Conn, P. Jeffrey,Lindsley, Craig W.,Hopkins, Corey R.,Niswender, Colleen M.,Gogliotti, Rocco D.,Engers, Darren W.,Cheung, Yiu-Yin,Salovich, James M.
申请号:
AU2013202881
公开号:
AU2013202881A1
申请日:
2013.04.08
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
#$%^&*AU2013202881A120130502.pdf#####ABSTRACT Pyrazolopyridine, pyrazolopyrazine, pyrazolopyrimidine, pyrazolothiophene and pyrazolothiazole compounds which are useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4) 5 synthetic methods for making the compounds pharmaceutical compositions comprising the compounds and methods of using the compounds, for example, in treating neurological and psychiatric disorders or other disease state associated with glutamate dysfunction.