Disclosed is a pharmaceutical composition comprising as an active ingredient an isolated population of cell suspension from a mammalian fetal pulmonary tissue, wherein said fetal pulmonary tissue is at a developmental stage corresponding to that of a human pulmonary organ/tissue at a gestational stage selected from a range of 20-22 weeks of gestation. Also disclosed is the use of said a pharmaceutical composition for the manufacture of a medicament for treating a disease or condition in which regeneration of epithelial, mesenchymal and/or endothelial tissue is beneficial in a subject and for treating a pulmonary disorder or injury in a subject.