The invention relates to the system and method of remote ECG monitoring, remote disease screening, and early-warning system based on wavelet analysis. The system includes a wireless ECG signal acquisition device, a mobile terminal, and a cloud storage platform. The wireless ECG signal acquisition device worn on the user's chest is used to collect ECG signals anywhere and anytime. The method includes transmitting the ECG signals to the mobile terminal using the wavelet analysis algorithm, analyzing and processing the received ECG signal, and uploading the processed ECG signals to the cloud storage platform. The cloud storage platform stores users' personal information and ECG signals. According to the ECG features detection with support vector machine learning algorithm for heart diseases diagnosis and features classification, the system gives feedback report and proposal, and transmits them to the mobile terminal.