glucagon compound of the peptide superfamily exhibiting g receptor activity with coupled protein, prodrug, dimer or multimer, pharmaceutical composition comprising it and method of administration thereof.
Indiana University Research and Technology Corporation
发明人:
Dimarchi, Richard, D,Zhang, Lianshan
申请号:
BR112012028707
公开号:
BR112012028707A2
申请日:
2011.05.10
申请国别(地区):
BR
年份:
2019
代理人:
摘要:
Provided herein are glucagon superfamily peptides conjugated with GPCR ligands that are capable of acting at a G protein-coupled receptor. Also provided herein are pharmaceutical compositions and kits of the conjugates of the invention. Further provided herein are methods of treating a disease, e.g., a metabolic disorder, such as diabetes and obesity, comprising administering the conjugates of the invention.