A device drug delivery (100) comprising: a body (104, 116), including an upper enclosure (116) and a lower enclosure (104), the lower enclosure (104) having a surface including a coupling button guide (268) a tank (160) disposed within the body (104, 116) for containing a medicament an injection needle (152) to penetrate the patients skin, with the needle (152) and a lumen in communication with the reservoir (160) when the device (100) is activated pressurization system (140, 144) for pressurizing the reservoir (160) when the device (100) is activated and a trigger button (128) movably disposed on the body (104, 116) and movable from a pre-activated to an activated position, including the activation button (128) activation arm (228) position wherein when the actuator button (128) moves from the pre-activated to the activated position, position one end of the activation arm (228) engages the guide hooking button (268) and prevents return movement activator button from the activated position to the pre-activated, wherein the guide hooking button (268) comprises a guide surface (270) and a retaining surface (272) position the activation arm (228) includes a recess (260A, 260B) and a locking portion (256) and when the actuator button (128) moves from the pre-activated to the activated position, position the recess (260A, 260B) allows the activation arm (228) passing over one end of the guide surface (270) and locking portion (256) of the activation arm (228) engageable with the retaining surface (272) of guide hooking button (268).Un dispositivo de administración de fármaco (100), que comprende: un cuerpo (104, 116), que incluye un cerramiento superior (116) y un cerramiento inferior (104), teniendo el cerramiento inferior (104) una superficie que incluye un enganche de guía de botón (268) un depósito (160) dispuesto dentro del cuerpo (104, 116) para contener un medicamento una aguja de inyección (152) para penetrar la piel del paciente, teniendo la aguja (152) un lumen