SMITH, Ernest S.,ZAUDERER, Maurice,BOWERS, William J.,JONASON, Alan
申请号:
AU2019257379
公开号:
AU2019257379A1
申请日:
2019.10.28
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
#$%^&*AU2019257379A120191114.pdf#####ABSTRACT Provided are methods for alleviating symptoms in a subject having a neurodegenerative disorder, comprising administering to the subject an effective amount of an isolated binding molecule which specifically binds to semaphorin-4D (SEMA4D) or to its Plexin-B 1 or PlexinB2 receptors. Further provided is an isolated binding molecule which specifically binds to the same SEMA4D epitope as a reference monoclonal antibody selected from the group consisting of VXl 5/2503 and 67.