2. The method of reducing zimens content in plasma protein component and / or protein SERINA protein. In addition, a method for producing protein components is provided, which are composed of a low content protein SERINA protein and / or a protein SERINA zimmes. This product provides, inter Alia, water and lymphoprotein compounds produced by plasma containing a small amount of protein SERINA protein and / or protein SERINA protein zimmes. Other aspects include treatment methods,1. Treatment and / or prevention of a disease, including the management of the protein SERINA protein or the plasma protein component with low content of SERINA protein in Zimbabwe. Retificas 1: a method of reducing the protein SERINA protein or the protein component Zimon of SERINA protein in the protein component 2. Derivatives from related plasmas, characterized in that the method comprises the following steps: (a) contacting the components with silica (SiO2) finely divided and having suitable conditions to polymerize zimmen of at least a series of proteins or a SERINA proteinase；And (b) the SiO2 is separated from the component to remove the polymerized ammonia enzyme SERINA, in which at least one SERINA protesa or Zimon de SERINA protesa is the Xia (fxia) factor,Xlia (fxia) factor,Factor eleven (FXI) or factor twelve (FXII).Métodos para reducir el contenido de zimógenos de serina proteasas y/o de serina proteasas en una composición de proteínas derivada de plasma. También se proveen métodos de elaboración de composiciones de proteínas derivadas de plasma con un contenido reducido de serina proteasas y/o de zimógenos de serina proteasas. Entre otros aspectos, la presente provee composiciones acuosas y liofilizadas de proteínas derivadas de plasma con un contenido reducido de serina proteasas y/o de zimógenos de serina proteasas. Otros aspectos incluyen métodos para tratar, manejar y/o prevenir una enfermedad que comprenden administrar una composición de proteínas derivadas de plasma con un
