An enema device for washing a large intestine that can supply water to a large intestine to easily wash and defecate the large intestine. The enema device for washing a large intestine includes a nozzle part inserted into an anal passage and having an ejection hole for ejecting water at one end thereof; a balloon part coupled to an outer peripheral surface of the nozzle part to be expanded; an air pump configured to supply air to the balloon part; a switching valve, to which the air pump is connected; a first water hose, an air hose, and a second water hose; the nozzle part has a discharge hole through which air supplied from the air hose is discharged to the balloon part.