AN IN SITU METHOD FOR MEASURING DEPOSITION OF AN ORAL AGENT FROM A DENTIFRICE ON A SUBSTRATE AND A METHOD FOR EVALUATING THE EFFECTIVENESS OF AN ORAL DELIVERY SYSTEM
Improved analytical, diagnostic, monitoring, and other methods (and their associated devices) for evaluating the extent of deposition of an agent onto a substrate are described. Exemplary methods may be used in the monitoring of the dental health of patients or in the fast, efficient screening and/or characterization of formulations in terms of their use for depositing oral actives onto tooth surfaces. The methods involve the direct orin situanalysis of substrates, onto which agents are deposited, using Near-IR spectroscopy and/ or UV spectroscopy.本發明揭露一種分析、診斷,與監控之改良方法(以及其相關裝置),其用以評估基材上之藥劑沉積程度。示範方法能夠用來監控患者的口腔健康,或者當用於在牙齒表面沉積口腔活性物質時,有效率地快速篩選以及/或者了解化學式的特徵。本方法包涵使用近紅外線頻譜分析儀(Near-IR spectroscopy)以及/或紫外線頻譜分析儀(UV spectroscopy),來進行基材的直接分析或原位(in situ)分析,其中之基材上具有沉積於其上之藥劑。110...中央處理器300...牙刷/探針301...刷頭302...握把303...潔牙元件305...診斷性感測系統307...光照裝置
