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FORMULACION EN FORMA DE TABLETA DE 2-FLUOR-N-METIL-4-[7-(QUINOLIN-6-YLMETIL)IMIDAZO[1,2- B][1,2,4]TRIAZIN-2-IL]BENZAMIDA
专利权人:
NOVARTIS AG
发明人:
GONCALVES, ELISABETE,TAUCHMANN, CHRISTIN,YEN, SHAU-FONG,VIPPAGUNTA, SUDHA,ZONG, ZHIXIN
申请号:
PE0000972017
公开号:
PE05232017A1
申请日:
2015.07.22
申请国别(地区):
PE
年份:
2017
代理人:
摘要:
Refers to a Formulation in the form of Tablet Comprising 2 - fluoro - N - methyl - 4 - (6 - [7 - quinolin-1 - ylmethyl) imidazo [1,2-b] [1,2,4] triazin - 2 - il) benzamide or a pharmaceutically acceptable Salt thereof.Also includes 10% - 30% by weight of 2 - fluoro - N - methyl - 4 - (6 - [7 - quinolin-1 - ylmethyl) imidazo [1,2-b] [1,2,4] triazin - 2 - il) benzamide or a pharmaceutically acceptable Salt thereof, 50% - 70% of one or more agents Filler, 3% - 20% of one or more disintegrant 0.2% - 2% of one or more Lubricants and 0.2% - 2% of one or m As Sliding. Also refers to a process.This formulation Inhibits the kinase c-met, being useful in the treatment of Lung Cancer, Liver, among othersSe refiere a una formulacion en forma de tableta que comprende 2-fluoro-N-metil-4-[7-(quinolin-6-ilmetil)imidazo[1,2-b][1,2,4]triazin-2-il)benzamida o una sal farmaceuticamente aceptable del mismo. Ademas comprende 10%-30% en peso de 2-fluoro-N-metil-4-[7-(quinolin-6-ilmetil)imidazo[1,2-b][1,2,4]triazin-2-il)benzamida o una sal farmaceuticamente aceptable del mismo, 50%-70% de uno o mas agentes de relleno, 3%-20% de uno o mas disgregantes 0,2%-2% de uno o mas lubricantes y 0,2%-2% de uno o mas deslizantes. Tambien se refiere a un proceso. Dicha formulacion inhibe las quinasas c-Met, siendo util en el tratamiento de cancer de pulmon, higado, entre otros
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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