The invention relates to a surgical instrument (1) with an elongate body (2) with a longitudinal axis (3) having a distal end (4) and a proximal end (11). The instrument has a pitch capstan (22,34) having an axis (17,20) transversely to the longitudinal axis (3) at one end of the elongate body. At least two pairs of cables (27,28;29,30) extend along the elongate body (2), along the pitch axis (17,20) to a respective work member (5,6;14,15) to which they are attached. The invention is characterized in that, the cables (27,28;29,30) are guided in sliding contact along a slide bearing (22,34,42,43) situated at or near the pitch axis (17,20). The invention also relates to a handle (10) for a medical instrument having a hinging connection (18, 31,32,34,35) with the elongate body situated near an inside hand region of the user.