Cosmetic or dermatological composition (I) for promoting the migration of cells, preferably keratinocytes, comprises active ingredient, and natural or synthetic opal powder having a diameter of 10-800 nm, mixed or in combination with an excipient or vehicle. An independent claim is included for a cosmetic treatment of the skin comprising inducing migration of cells towards the opal particles to obtain the migration of cells in tissues with cell depletion. ACTIVITY : Dermatological. MECHANISM OF ACTION : None given.