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Anti-TYRP1 antibodies
专利权人:
ImClone LLC
发明人:
Balderes, Paul J.,Kang, Xiaoqiang
申请号:
AU2009222998
公开号:
AU2009222998B2
申请日:
2009.03.11
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The present invention provides for fully human antibodies and chimeric antibodies that bind human TYRP1 antigen with an affinity comparable to or higher than TA99, a murine antibody specific to TYRP1. The invention further provides polynucleic acids and host cells that encode and express these antibodies. The invention also provides for methods of modulating activity of TYRP1, treating growth of a cancer cell, and treating a malignant melanoma in mammals by administering an effective amount of an antibody either alone or in combination with an anti-cancer agent or treatment.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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