Ben-Gurion University of the Negev Research and Development Authority
发明人:
Yaffa Mizrachi Nebenzahl
申请号:
US13734350
公开号:
US20130108659A1
申请日:
2013.01.04
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Vaccine compositions and methods for protecting a mammalian subject against infection with S. pneumoniae are disclosed. The vaccines and methods comprise an effective amount of one or more Streptococcus pneumoniae cell wall and/or cell membrane proteins and/or immunogenically-active fragments, derivatives or modifications thereof, wherein the proteins are selected from a defined group of proteins associated with age-dependent immunological responses.