MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG
发明人:
SCHIEMANN, KAI,BOETTCHER, HENNING,LEIBROCK, JOACHIM
申请号：
CA2445835
公开号：
CA2445835C
申请日:
2002.04.05
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
Compounds of the formula I in which R1, R2, R3 and R4 are as defined in Claim1, are ligands of the nicotinic acetylcholine receptor and/or serotonergicligands and are suitable for the prophylaxis or treatment of psychoses,schizophrenia, depression, anxiety states, dementia, in particular Alzheimer'sdisease and Lewy bodies dementia, neurodegenerative disorders, Parkinson'sdisease, amyotrophic lateral sclerosis, Huntington's disease, Tourette'ssyndrome, learning and memory restrictions, bulimia anorexia nervosa or othereating disorders, compulsvie behaviour, premenstrual syndrome, age-inducedmemory impairment, amelioration of withdrawal symptoms in nicotine dependence,strokes or brain damage by toxic compounds, and for the treatment of disorderswhich are characterised by an excess of circulating serotonin or byserotonergic hyperactivity.
