HEPATITIS C VIRUS NUCLEIC ACID VACCINE

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专利权人:

ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A.

发明人:

LAHM, ARMIN,COLLOCA, STEFANO,FOLGORI, ANTONELLA,NICOSIA, ALFREDO

申请号：

CA2610919

公开号：

CA2610919C

申请日:

2006.06.13

申请国别(地区):

CA

年份:

2013

代理人:

摘要：

The present invention features nucleic acid constructs that can be used as aHCV nucleic acid vaccine, vaccine component, or in the production of a HCVvaccine. Described constructs include those: (1) encoding for a chimeric HCVpolypeptide containing a NS3-4A region based on a first HCV strain and an NS3-NS4A-NS4B-NS5A or an NS3-NS4A-NS4B-NS5A-NS5B region based on a second strainand (2) a chimpanzee based adenovector encoding an HCV polypeptide.

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http://www.ckcest.cn/home/