The present invention relates to the field of (vector) vaccines, and especially to a canine distemper virus (CDV) vector comprising a heterologous nucleotide sequence which encodes a porcine epidemic diarrhea virus (PEDV) antigen. Said PEDV antigen is preferably a PEDV spike (S) protein. The viral vector of the present invention is useful for producing an immunogenic composition or vaccine for intranasally immunizing sows, and thereby protecting piglets, suckled by said sows, against the clinical signs associated with a PEDV infection.本發明係關於(載體)疫苗之領域，且尤其係關於包含編碼豬流行性下痢病毒(PEDV)抗原之異源核苷酸序列的犬瘟熱病毒(CDV)載體。該PEDV抗原較佳係PEDV棘(S)蛋白。本發明之該病毒載體可用於產生免疫原性組合物或疫苗以用於對母豬進行鼻內免疫，且藉此保護由該等母豬哺育之仔豬對抗與PEDV感染相關之臨床徵象。
