Association comprises: agomelatine (N-[2-(7-methoxy-1-naphtyl)ethyl]acetamide) or its hydrate, crystalline, acid or base salts; and thymoregulating agent. ACTIVITY : Hypnotic; Antidepressant; Cardiovascular-Gen; Neuroleptic; Anorectic; Gastrointestinal-Gen; CNS-Gen. MECHANISM OF ACTION : Melatoninergic receptor system agonist; Hydroxytryptamine receptor antagonist.