DOMINGUEZ Esteban,GUO Deqi,MADER Mary Margaret,NGUYEN Anh-Quan Hannah,DEL PRADO Miriam Filadelfa,RICHETT Michael Enrico,RODRIGUEZ Michael John,YIP Yvonne Yee Mai,YU Kuo-Long
申请号：
MDE20180644
公开号：
MD3341379T2
申请日:
2016.08.22
申请国别(地区):
MD
年份:
2020
代理人:
摘要：
This invention refers to compounds that inhibit the histone activity of lysimethyltransferase, Enhancer of Zeste homologue 2(EZH2)), to pharmaceutical compositions containing compounds, and to methods of use of cancer treatments, such as haematological and solid tumours.Prezenta invenţie se referă la compuşi care inhibă activitatea histon lizinmetiltransferazei, amplificator al omologului Zeste (Enhancer of Zeste Homolog 2(EZH2)), la compoziţii farmaceutice care cuprind compuşii, şi la metode de utilizare acompuşilor pentru tratarea cancerului, cum ar fi tumori hematologice şi solide.
