Provided herein are methods for treating subjects having a cancer, such as a relapsed or refractory solid tumor, wherein the method comprises administering to the subject a cytidine analog. In certain of the methods, the cytidine analog is administered alone or in combination with one or more anti-cancer agents. Also provided are methods for using a cytidine analog, to treat diseases and disorders including disorders related to abnormal cell proliferation, hematologic disorders, and immune disorders, among others. In certain of the methods, the cytidine analog is formulated in an oral dosage form and administered orally.本發明提供治療患有諸如復發性或難治性實體腫瘤等癌症之個體之方法,其中該方法包含向該個體投與胞嘧啶核苷類似物。在某些該等方法中,該胞嘧啶核苷類似物單獨或與一或多種抗癌劑組合投與。本發明亦提供使用胞嘧啶核苷類似物治療疾病及病症之方法,該等疾病及病症包括與異常細胞增殖相關之病症、血液學病症及免疫病症等。在某些該等方法中,該胞嘧啶核苷類似物調配成口服劑型並口服投與。
