Disclosed are: a method for inducing the differentiation of stein cells into tissue cells a bioartificial organ which comprises the tissue cells and a material for medical purposes which comprises the bioartificial organ. Stem cells capable of pro�liferation self-replication and differentiation are used and cultured by a hanging-drop method to three-dimensionally construct a cell mass of embryoid bodies and the cell mass is cultured in the presence of HGF GDNF b-FGF BMP7 and EGF. In this man�ner the stem cells can be differentiated into tissue cells. A bioartificial organ can be produced using cells that have been differentiated into the tissue cells. Further a material for medical purposes can be provided.
