BEXION PHARMACEUTICALS, INC.;UNVERSITY OF CINCINNATI
发明人:
QI, XIAOYANG,OLOWOKURE, OLUGBENGA,TAKIGIKU, RAY
申请号：
CA3047936
公开号：
CA3047936A1
申请日:
2017.11.21
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Disclosed herein, according to the present invention, are methods of treating pancreatic cancer comprising administering a first pharmaceutical composition comprising Saposin C and dioleoylphosphatidylserine (SapC-DOPS) and administering a second pharmaceutical composition comprising an anti-neoplastic agent. Optionally, additional pharmaceutical compositions may be administered. Also disclosed are methods of inhibiting tumor growth. Also disclosed are kits for the treatment of pancreatic cancer comprising at least two pharmaceutical compositions, wherein a first pharmaceutical composition comprises SapC-DOPS and wherein a second pharmaceutical composition comprises a first antineoplastic agent. Also disclosed herein are combination therapeutics comprising a first pharmaceutical composition comprising SapC-DOPS and at least a second pharmaceutical composition comprising an antineoplastic agent, wherein the first and second pharmaceutical compositions are formulated separately to be used in the form of a kit where they are present together.
