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Modulators of Cystic Fibrosis Transmembrane Conductance Regulator
专利权人:
VERTEX PHARMACEUTICALS INCORPORATED
发明人:
Mark Thomas Miller,Corey Anderson,Vijayalaksmi Arumugam,Brian Richard Bear,Hayley Marie Binch,Jeremy J. Clemens,Thomas Cleveland,Erica Conroy,Timothy Richard Coon,Bryan A. Frieman,Peter Diederik Jan G
申请号:
US14876525
公开号:
US20160095858A1
申请日:
2015.10.06
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention features a compound of formula I:or a pharmaceutically acceptable salt thereof, where R1, R2, R3, W, X, Y, Z, n, o, p, and q are defined herein, for the treatment of CFTR mediated diseases, such as cystic fibrosis. The present invention also features pharmaceutical compositions, method of treating, and kits thereof.
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