An integrated electronic device, and its method of manufacture, are provided. The integrated electronic device can include Iontophoresis electrodes that are electrically coupled to a thin printed flexible electrochemical cell. In one example, the Iontophoresis electrodes and the electrochemical battery are provided on a single substrate. In one example method of manufacture, the entire cell can be made on a printing press to integrate the battery directly with the electronic assembly of the Iontophoresis electrodes.