ERAP1-derived peptides and uses thereof

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专利权人:

国立大学法人徳島大学;オンコセラピー・サイエンス株式会社

发明人:

片桐 豊雅,角田 卓也

申请号：

JP2013526881

公开号：

JP6014904B2

申请日:

2012.07.27

申请国别(地区):

JP

年份:

2016

代理人:

摘要：

Provided is a novel cancer-treating agent which can be used as a novel choice for the treatment of cancer. Specifically provided are: a peptide that inhibits binding of ERAP1 polypeptide to PHB2 polypeptide, which comprises a binding site of the ERAP1 polypeptide to the PHB2 polypeptide, and a pharmaceutical composition comprising the peptide. In addition, provided is a method for screening a drug candidate for treating and/or preventing cancer using inhibition of the binding of the ERAP1 polypeptide to PP1± polypeptide, PKA polypeptide or PKB polypeptide as an index.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/