Robert D. Miller,Victoria A. Piunova,William C. Swope
申请号:
US15334492
公开号:
US10392470B2
申请日:
2016.10.26
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Amphiphilic star polymers were prepared having superior loading properties for delivery of hydrophobic biologically active materials intended for use in medical, cosmetic, and other applications. The star polymers comprise a plurality block copolymer arms linked to a crosslinked polyester core. The monovalent arms comprise a peripheral poly(ethylene oxide) block (PEG block) and a polyester block, which is linked to the core. The sidechain substituents of the polyester block substantially improve the loading capacity of the star polymer for CoQ10 and other hydrophobic materials.