David Simpson,Gary Bowlin,Raymond Colello,Woon Chow,Balendu Shekhar Jha
申请号:
US13394415
公开号:
US20120221025A1
申请日:
2010.09.14
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Nerve guides which are formed from three dimensional (3D) arrays of highly aligned electrospun fibers are provided. The electrospun fibers are oriented parallel to the long axis of the guide, and gaps and elongated spaces between the stacked fiber arrays provide channels for directed axonal growth. In some embodiments, the nerve guides also comprise high precision gradients of beneficial substances such as growth factors, which aid in nerve regeneration and growth along the guide.