The invention relates to substituted dihydropyrazolo pyrazine carboxamide derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and diabetes, and also urogenital and ophthalmic disorders.本發明是關於經取代的二氫吡唑并吡甲醯胺衍生物及其製備方法,還關於其等用於製備治療及/或預防疾病的藥物的用途,特別是心血管疾病,較佳是血栓形成或血栓栓塞性疾病、糖尿病、還有泌尿生殖系統及眼科疾病。