Methods, devices, and systems for determining an estimated pulse wave velocity of an artery of a subject. Embodiment methods may include applying a series of counter pressures, measuring a first parameter related to pulse wave velocity, estimating a second parameter in a model, and determining the estimated pulse wave velocity. The counter pressures may be applied at a set location on the subject over the artery with a pressure device. Each of the counter pressures may be different from one another, applied at the set location, and between zero and a diastolic pressure of the subject. The first parameter may be measured when each of the series of counter pressures is applied. The model may establish a relationship of the first parameter measured to each of the series of counter pressures. The estimated pulse wave velocity may be determined based on the second parameter estimated in the model.
